However, the prolonged use of traditional topical and/or systemic antibiotics to suppress recolonization may be impractical given potential concerns about increased antibiotic resistance from long-term antibiotic use 10, 11.īleach (sodium hypochlorite, NaOCl) baths are an inexpensive, widely accessible, alternative antibiotic treatment that may not worsen antibiotic resistance 12. aureus colonization and microbiome in AD, anti-bacterial treatments have been considered for managing AD 9. aureus overgrowth even without frank infection 5, 7, 8. aureus infection, and AD exacerbations may be induced by S. aureus density AD flares are associated with cutaneous S. In particular, AD severity is correlated with epidermal S. aureus colonization compared with healthy controls (>70% vs. AD is associated with a higher prevalence of epidermal S. xerosis and pruritus) and predisposing patients to cutaneous infections. Deficiencies in the epidermal barrier and dysfunction of the immune system contribute to AD pathogenesis, resulting in the characteristic signs and symptoms of AD (e.g. Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder affecting 15–20% of children and 1–10% of adults in the United States and worldwide 1– 4.
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